SLC9A4 (NM_001011552) Human Untagged Clone
CAT＃: SC301580
SLC9A4 (untagged)-Human solute carrier family 9 (sodium/hydrogen exchanger), member 4 (SLC9A4)
CNY 15390.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | NHE4 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC301580 representing NM_001011552.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCTCTGCAGATGTTCGTGACTTACAGTCCTTGGAATTGTTTGCTACTGCTAGTGGCTCTTGAGTGT TCTGAAGCATCTTCTGATTTGAATGAATCTGCAAATTCCACTGCTCAGTATGCATCTAACGCTTGGTTT GCTGCTGCCAGCTCAGAGCCAGAGGAAGGGATATCTGTTTTTGAACTGGATTATGACTATGTGCAAATT CCTTATGAGGTCACTCTCTGGATACTTCTAGCATCCCTTGCAAAAATAGGCTTCCACCTCTACCACAGG CTGCCAGGCCTCATGCCAGAAAGCTGCCTCCTCATCCTGGTGGGGGCGCTGGTGGGCGGCATCATCTTC GGCACCGACCACAAATCGCCTCCGGTCATGGACTCCAGCATCTACTTCCTGTATCTCCTGCCACCCATC GTTCTGGAGGGCGGCTACTTCATGCCCACCCGGCCCTTCTTTGAGAACATCGGCTCCATCCTGTGGTGG GCAGTATTGGGGGCCCTGATCAACGCCTTGGGCATTGGCCTCTCCCTCTACCTCATCTGCCAGGTGAAG GCCTTTGGCCTGGGCGACGTCAACCTGCTGCAGAACCTGCTGTTCGGCAGCCTGATCTCCGCCGTGGAC CCAGTGGCCGTGCTAGCCGTGTTTGAGGAAGCGCGCGTGAACGAGCAGCTCTACATGATGATCTTTGGG GAGGCCCTGCTCAATGATGGCATTACTGTGGTCTTATACAATATGTTAATTGCCTTTACAAAGATGCAT AAATTTGAAGACATAGAAACTGTCGACATTTTGGCTGGATGTGCCCGATTCATCGTTGTGGGGCTTGGA GGGGTATTGTTTGGCATCGTTTTTGGATTTATTTCTGCATTTATCACACGTTTCACTCAGAATATCTCT GCAATTGAGCCACTCATCGTCTTCATGTTCAGCTATTTGTCTTACTTAGCTGCTGAAACCCTCTATCTC TCCGGCATCCTGGCAATCACAGCCTGCGCAGTAACAATGAAAAAGTACGTGGAAGAAAACGTGTCCCAG ACATCATACACGACCATCAAGTACTTCATGAAGATGCTGAGCAGCGTCAGCGAGACCTTGATCTTCATC TTCATGGGTGTGTCCACTGTGGGCAAGAATCACGAGTGGAACTGGGCCTTCATCTGCTTCACCCTGGCC TTCTGCCAAATCTGGAGAGCCATCAGCGTATTTGCTCTCTTCTATATCAGTAACCAGTTTCGGACTTTC CCCTTCTCCATCAAGGACCAGTGCATCATTTTCTACAGTGGTGTTCGAGGAGCTGGAAGTTTTTCACTT GCATTTTTGCTTCCTCTGTCTCTTTTTCCTAGGAAGAAAATGTTTGTCACTGCTACTCTAGTAGTTATA TACTTTACTGTATTTATTCAGGGAATCACAGTTGGCCCTCTGGTCAGGTACCTGGATGTTAAAAAAACC AATAAAAAAGAATCCATCAATGAAGAGCTTCATATTCGTCTGATGGATCACTTAAAGGCTGGAATCGAA GATGTGTGTGGGCACTGGAGTCACTACCAAGTGAGAGACAAGTTTAAGAAGTTTGATCATAGATACTTA CGGAAAATCCTCATCAGAAAGAACCTACCCAAATCAAGCATTGTTTCTTTGTACAAGAAGCTGGAAATG AAGCAAGCCATCGAGATGGTGGAGACTGGGATACTGAGCTCTACAGCTTTCTCCATACCCCATCAGGCC CAGAGGATACAAGGAATCAAAAGACTTTCCCCTGAAGATGTGGAGTCCATAAGGGACATTCTGACATCC AACATGTACCAAGTTCGGCAAAGGACCCTGTCCTACAACAAATACAACCTCAAACCCCAAACAAGTGAG AAGCAGGCTAAAGAGATTCTGATCCGCCGCCAGAACACCTTAAGGGAGAGCATGAGGAAAGGTCACAGC CTGCCCTGGGGAAAGCCGGCTGGCACCAAGAATATCCGCTACCTCTCCTACCCCTACGGGAATCCTCAG TCTGCAGGAAGAGACACAAGGGCTGCTGGGTTCTCAGATGATGACAGCAGTGATCCAGGATCCCCATCC ATCACGTTCAGCGCATGCTCTCGGATAGGGTCACTTCAGAAGCAAGAGGCACAAGAAATAATACCAATG AAGAGCCTACACAGAGGAAGGAAGGCATTCAGCTTTGGTTATCAAAGAAACACAAGCCAAGAAGAGTAC TTGGGTGGAGTAAGGAGGGTGGCCTTAAGACCCAAACCTCTGTTTCATGCAGTGGATGAGGAGGGTGAG TCTGGAGGGGAGAGTGAGGGCAAGGCCTCTTTGGTTGAGGTTCGGTCGAGGTGGACAGCTGACCATGGA CACGGCAGGGACCATCACAGGTCCCATAGTCCTTTGCTCCAAAAAAAATAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001011552 |
| Insert Size | 2397 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001011552.3 |
| RefSeq Size | 4174 bp |
| RefSeq ORF | 2397 bp |
| Locus ID | 389015 |
| UniProt ID | Q6AI14 |
| Protein Families | Druggable Genome, Transmembrane |
| MW | 89.8 kDa |
| Gene Summary | Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. May play a specialized role in the kidney in rectifying cell volume in response to extreme fluctuations of hyperosmolar-stimulated cell shrinkage. Is relatively amiloride and ethylisopropylamiloride (EIPA) insensitive. Can be activated under conditions of hyperosmolar-induced cell shrinkage in a sustained intracellular acidification-dependence manner. Activated by 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS) in a sustained intracellular acidification-dependence manner. Affects potassium/proton exchange as well as sodium/proton and lithium/proton exchange. In basolateral cell membrane, participates in homeostatic control of intracellular pH, and may play a role in proton extrusion in order to achieve transepithelial HCO3(-) secretion. In apical cell membrane may be involved in mediating sodium absorption. Requires for normal levels of gastric acid secretion, secretory membrane development, parietal cell maturation and/or differentiation and at least secondarily for chief cell differentiation (By similarity).[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212529 | SLC9A4 (Myc-DDK-tagged)-Human solute carrier family 9 (sodium/hydrogen exchanger), member 4 (SLC9A4) |
CNY 5848.00 |
|
| RC212529L3 | Lenti ORF clone of Human solute carrier family 9 (sodium/hydrogen exchanger), member 4 (SLC9A4), Myc-DDK-tagged |
CNY 10360.00 |
|
| RC212529L4 | Lenti ORF clone of Human solute carrier family 9 (sodium/hydrogen exchanger), member 4 (SLC9A4), mGFP tagged |
CNY 10360.00 |
|
| RG212529 | SLC9A4 (tGFP-tagged) - Human solute carrier family 9 (sodium/hydrogen exchanger), member 4 (SLC9A4) |
CNY 9310.00 |
