ZNF683 (NM_173574) Human Untagged Clone
CAT＃: SC306864
ZNF683 (untagged)-Human zinc finger protein 683 (ZNF683), transcript variant 2
CNY 7220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Hobit |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_173574, the custom clone sequence may differ by one or more nucleotides
ATGAAGGAAGAATCAGCTGCACAATTAGGTTGTTGTCATAGGCCCATGGCCCTGGGAGGT ACAGGGGGCTCCCTGTCCCCCAGCCTGGACTTCCAGCTCTTCCGAGGTGACCAGGTCTTC TCAGCCTGCAGACCACTTCCAGACATGGTGGATGCTCATGGCCCATCCTGTGCCAGCTGG CTGTGTCCCTTGCCCCTGGCACCGGGCAGGTCTGCACTGCTGGCCTGCCTACAGGACCTG GACCTGAACCTGTGCACCCCACAGCCGGCACCCCTGGGCACAGACCTGCAGGGCCTCCAA GAGGACGCCTTGAGCATGAAGCACGAGCCACCAGGGCTGCAGGCCAGCTCCACCGATGAC AAGAAATTCACAGTCAAGTACCCACAGAACAAGGACAAGCTGGGAAAACAGCCAGAAAGA GCTGGCGAGGGGGCCCCCTGCCCAGCCTTCTCCTCTCATAACAGCTCTTCCCCACCACCG CTGCAGAACAGAAAGAGCCCCAGCCCCTTGGCTTTCTGCCCCTGTCCCCCTGTCAACTCC ATCTCCAAGGAGCTCCCATTTCTCCTCCACGCCTTCTACCCTGGATACCCACTTCTCCTG CCTCCACCCCACCTGTTCACCTATGGGGCCCTACCTTCTGACCAATGTCCCCACCTCCTC ATGCTGCCCCAAGACCCCTCCTACCCCACCATGGCTATGCCTAGCCTGCTGATGATGGTC AATGAGCTGGGGCACCCCAGCGCTCGGTGGGAGACCCTGCTTCCCTACCCAGGGGCCTTC CAAGCCTCTGGCCAAGCTCTGCCTTCCCAGGCCCGAAATCCAGGTGCTGGAGCTGCCCCA ACCGACTCCCCAGGCCTGGAGCGTGGTGGCATGGCATCTCCAGCAAAGCGGGTCCCATTG AGTTCCCAGACAGGCACCGCAGCCTTGCCTTACCCGCTGAAAAAGAAGAATGGCAAAATC CTGTACGAGTGCAACATATGTGGCAAGAGCTTTGGGCAGCTCTCCAATCTCAAGGTCCAC CTGCGTGTGCACAGTGGAGAGCGTCCATTCCAGTGTGCCTTGTGCCAGAAGAGCTTCACT CAACTTGCCCACCTGCAGAAGCACCACCTGGTGCACACTGGGGAGCGGCCCCACAAGTGC TCGGTGTGCCACAAGCGCTTCAGCAGCTCCAGTAACCTCAAGACCCACCTGCGCCTGCAC TCCGGGGCCCGGCCCTTCCAGTGCAGTGTCTGCCGGAGTCGCTTCACCCAGCACATCCAC CTGAAGCTGCACCATCGGCTGCATGCCCCACAGCCCTGTGGCCTGGTGCACACCCAGCTG CCCCTGGCCTCTCTGGCCTGCCTTGCCCAATGGCACCAGGGGGCACTAGATCTTATGGCG GTGGCATCTGAGAAACACATGGGCTATGACATAGATGAGGTCAAAGTGTCCTCGACATCC CAGGGGAAAGCAAGAGCAGTGAGCCTGAGCAGTGCCGGGACTCCCCTGGTGATGGGGCAG GACCAGAACAATTAA |
| Restriction Sites | Please inquire |
| ACCN | NM_173574 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_173574.1, NP_775845.1 |
| RefSeq Size | 1725 bp |
| RefSeq ORF | 1665 bp |
| Locus ID | 257101 |
| UniProt ID | Q8IZ20 |
| Protein Families | Transcription Factors |
| Gene Summary | Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T-cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Plays also a role in the differentiation of both thymic and peripheral NKT cells. Negatively regulates the accumulation of interferon-gamma (IFN-gamma) in NKT cells at steady state or after antigenic stimulation. Positively regulates granzyme B production in NKT cells after innate stimulation. Associates with the transcriptional repressor PRDM1/BLIMP1 to chromatin at gene promoter regions.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (1). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206157 | ZNF683 (Myc-DDK-tagged)-Human zinc finger protein 683 (ZNF683), transcript variant 2 |
CNY 3752.00 |
|
| RC206157L3 | Lenti-ORF clone of ZNF683 (Myc-DDK-tagged)-Human zinc finger protein 683 (ZNF683), transcript variant 2 |
CNY 6460.00 |
|
| RC206157L4 | Lenti-ORF clone of ZNF683 (mGFP-tagged)-Human zinc finger protein 683 (ZNF683), transcript variant 2 |
CNY 6460.00 |
|
| RG206157 | ZNF683 (tGFP-tagged) - Human zinc finger protein 683 (ZNF683), transcript variant 2 |
CNY 5040.00 |
