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CD46 (NM_172351) Human Untagged Clone
CAT＃: SC313213
CD46 (untagged)-Human CD46 molecule, complement regulatory protein (CD46), transcript variant c
CNY 3,656.00
CNY 6,180.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AHUS2; MCP; MIC10; TLX; TRA2.10 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_172351 edited
GGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCCCTGCTCGGCTGGCTCTCG GTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCC GGCCGCCGCGAGTGTCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATG GTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCACCAACATTTGAAGCTATG GAGCTCATTGGTAAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGT AAAAAAGGATACTTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCAT ACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACATGTCCATATATACGGGAT CCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCAC TTTATTTGTAATGAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAA GGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAAAAGGTTTTGTGTACACCA CCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTT GATGCAGTAACTTATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGA GAGAGCACGATTTATTGTGGTGACAATTCAGTGTGGAGTCGTGCTGCTCCAGAGTGTAAA GTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAA AAATTTTACTACAAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGC AGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCAAAGTGTCTT AAAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCT ACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCTGAGGAAGGAATACTT GACAGTTTGGATGTTTGGGTCATTGCTGTGATTGTTATTGCCATAGTTGTTGGAGTTGCA GTAATTTGTGTTGTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGCACATACCTA ACTGATGAGACCCACAGAGAAGTAAAATTTACTTCTCTCTGAGAAGGAGAGATGAGAGAA AGGTTTGCTTTTATCATTAAAAGGAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAG ACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCC AGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCA TGAGTGCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTT GATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAA TAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGAT ATGCTGTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATT TTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAA GATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTT AAAAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGG AATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTA ATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGT ATGTGTGGCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAAT TTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAG TGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCG TATGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCC TCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAAT AAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCT AGTAAAAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAA GCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGA TGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTAC TGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGC CACTGCATTTCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCAC AAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGA AGAATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTT CCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGA ATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTC GCAATTACTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACC AAATACTTTAATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTC ACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTA TTTTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAA TGACAGAAGCGTATATGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAA TGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAA ATCTGTTAAAATAAAATTGTACATTTGGAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_172351 unedited
CATCAATTTGTATACGACNACTATAGGCGGCCGCGACTTCGGCACGAGGGGATTGTTGCG TCCCATATCTGGACCCAGAAGGACTTCCCTGCTCGGCTGGCTCTCGGTTTCTCTGCTTTC CTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAGTG TCCCTTTCCTTCCTGGCGCTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTA CTCCTTCTCCGATGCCTGTGAGGAGCCACCAACATTTGAAGCTATGGAGCTCATTGGTAA ACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATACTT CTATATACCTCCTCTTGCCACCCATACTATTTGTGATCGGAATCATACATGGCTACCTGT CTCAGATGACGCCTGTTATAGAGAAACATGTCCATATATACGGGATCCTTTAAATGGCCA AGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGA GGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAAT TTGGAGCGGTAAGCCCCCAATATGTGAAAAGGTTCTGTGTACACCACCTCCAAAAATAAA AAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTGAGTATCTTGATGCAGTAACTTA TAGTTGGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTT ATTGGTGGTGACAATTCAGTGTGGGAGTCGTGCTGCTCCANAGTGTAAGTGGTCAAATGT CGATCTCCAGTAGTCGATAATGGAAACAGATATCAGGATTGGNAAAAAATTCTACTACAA GCANCAGCTATGTTTGATGCGATAAGGGTTTTACCTCGATGCAGCGACCATTGTCGTGAA GTACAGACTGGGATCCCCAGTCAAGTGNTC >OriGene 3' read for NM_172351 unedited
AGNANAGCACTGGGGNAGGGTCACAGGGATGCCACTTGGCTCTGTTCAGGAAAAGCTATG ACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTCCAAATGTACAATT TTATTTTAACAGATTTCAAGAGTCCATTTTTTAAAAAATGAGCAATAAAGAACCTCTATC AGTGATACTTCTCATTTTATAGCAAATACATTTTGGCAGCTTAAATTTTCTTTTTTTCAT ATACGCTTCTGTCATTTAAACAAACTTCCAGAGAAAACTGGTCTCTATCCCTTTAAGTAA CAAATTTGACAAAATACATATTTATACATATATAGATCTCTAATATAAATATTAAATTTG AAAAAATTCAAATGTGAAGCAGAAACTGCTATACAAGTATATTGTATAATATTTATTTTA TACATTAAAGTATTTGGTTGAATATACTTCAATTAGGTTTCTAAAAAACACCATTATCTG CTTCTTAGTAATTGCGACATTCTTGAAAAGCATGTGAAACGGGTATAAACTTCAACTCTG TGCTTAATTCAGAATTCCTGTTTGTTCTCCTCAAACTTTTATCTTCCTAAAGCATCTTGC CCGAGACTACAAAGGAAAGGAACATTTTCCGAGCACTATAAACATGTCCTTTGGACAGTA AAACAGTATTTATTCTTCTACACTCTTGATTTCCCAATCATATCTTCCTCAAGGCAATGT TTCCTTGGCCCAACTTTGGGCACCTAACCATAAAATTTCAAAACACACTTTTACACAGGG AAATAAAATGCGGGGGCACCCCCTGTTTTTCCCTCGGGGCTTCTTTAAAAAAAATCTGTG CTTAAGGACTCAATAAAGGTTGAATCTCCCTGA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_172351 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_172351.1, NP_758861.1 |
| RefSeq Size | 3326 bp |
| RefSeq ORF | 1134 bp |
| Locus ID | 4179 |
| UniProt ID | P15529 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Complement and coagulation cascades |
| Gene Summary | The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010] Transcript Variant: This variant (c) lacks an alternate in-frame exon compared to variant a, resulting in a shorter isoform (3) compared to isoform 1. |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221012 | CD46 (Myc-DDK-tagged)-Human CD46 molecule, complement regulatory protein (CD46), transcript variant c |
CNY 3,656.00 |
|
| RC221012L1 | Lenti ORF clone of Human CD46 molecule, complement regulatory protein (CD46), transcript variant c, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC221012L2 | Lenti ORF clone of Human CD46 molecule, complement regulatory protein (CD46), transcript variant c, mGFP tagged |
CNY 5,890.00 |
|
| RC221012L3 | Lenti ORF clone of Human CD46 molecule, complement regulatory protein (CD46), transcript variant c, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC221012L4 | Lenti ORF clone of Human CD46 molecule, complement regulatory protein (CD46), transcript variant c, mGFP tagged |
CNY 5,890.00 |
|
| RG221012 | CD46 (tGFP-tagged) - Human CD46 molecule, complement regulatory protein (CD46), transcript variant c |
CNY 4,370.00 |
