DENND2B (NM_139157) Human Untagged Clone
CAT＃: SC314522
ST5 (untagged)-Human suppression of tumorigenicity 5 (ST5), transcript variant 2
CNY 13780.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HTS1; p126; ST5 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_139157, the custom clone sequence may differ by one or more nucleotides
ATGACCATGACTGCCAACAAGAATTCCAGCATCACCCACGGAGCTGGTGGCACTAAAGCC CCTCGGGGGACTCTGAGCAGAAAATCCTTTGAGTTTGAGGATGCATCCAGTCTCCAGTCC CTGTACCCCTCTTCTCCCACTGAGAATGGTACTGAGAACCAACCCAAGTTTGGATCCAAA AGCACTTTAGAAGAAAATGCCTATGAAGATATTGTGGGAGATCTGCCCAAGGAGAATCCA TATGAGGATGTGGACTTAAAGAGCCGAAGAGCAGGACGAAAATCCCAGCAACTGTCTGAG AACTCCTTGGACTCTTTGCACAGGATGTGGAGTCCTCAGGACAGGAAGTACAACAGCCCG CCCACACAGCTTTCCCTGAAACCCAACAGCCAGTCCCTGCGCAGTGGGAACTGGTCAGAA AGGAAGAGCCACCGGCTGCCACGATTACCCAAGAGGCACAGCCATGACGACATGCTGCTG CTGGCTCAGCTGAGTCTGCCGTCCTCACCCTCCAGCCTCAATGAAGACAGCCTCAGCACC ACCAGCGAGCTGCTGTCCAGCCGCCGGGCCCGCCGCATTCCCAAGCTTGTCCAAAGAATT AACTCCATCTACAATGCCAAGAGAGGAAAGAAGAGATTAAAAAAGTTGTCTATGTCCAGC ATTGAAACAGCATCACTGAGAGATGAAAACAGTGAGAGCGAGAGCGACTCTGATGACAGG TTCAAAGCCCACACACAGCGCCTGGTCCACATCCAGTCGATGCTGAAGCGCGCCCCCAGC TATCGCACGCTGGAGCTGGAGCTGCTGGAGTGGCAGGAGCGGGAGCTTTTTGAGTACTTT GTGGTGGTGTCCCTCAAGAAGAAGCCATCGCGAAACACCTACCTCCCCGAAGTCTCCTAC CAGTTTCCCAAGCTGGACCGACCCACCAAGCAGATGCGAGAGGCAGAGGAAAGGCTCAAA GCCATTCCCCAGTTTTGCTTCCCTGATGCCAAGGACTGGCTTCCTGTGTCAGAGTATAGC AGTGAGACCTTTTCTTTCATGCTGACTGGGGAAGATGGCAGCAGACGCTTTGGCTACTGC AGGCGCTTACTGCCAAGTGGGAAAGGGCCCCGGTTGCCAGAGGTGTACTGTGTCATCAGC CGCCTTGGCTGCTTCGGCTTGTTTTCCAAGGTCCTAGATGAGGTGGAGCGCCGGCGTGGG ATCTCCGCTGCATTGGTCTATCCTTTCATGAGAAGTCTCATGGAGTCGCCCTTCCCAGCC CCAGGGAAGACCATCAAAGTGAAGACATTCCTGCCAGGTGCTGGCAATGAGGTGTTAGAG CTGCGGCGGCCCATGGACTCAAGGCTGGAGCACGTGGACTTTGAGTGCCTTTTTACCTGC CTCAGTGTGCGCCAGCTCATCCGAATCTTTGCCTCACTGCTGCTGGAGCGCCGGGTCATT TTTGTGGCAGATAAGCTCAGTACCCTCTCCAGCTGCTCCCACGCGGTGGTGGCCTTGCTC TACCCCTTCTCCTGGCAGCACACCTTCATTCCTGTCCTCCCGGCCTCCATGATTGACATC GTCTGCTGTCCCACCCCCTTCCTGGTTGGCCTGCTCTCCAGCTCCCTCCCCAAACTGAAG GAGCTGCCTGTGGAGGAGGCGCTGATGGTGAATCTGGGATCTGACCGATTCATCCGACAG ATGGACGACGAAGACACGTTGTTACCTAGGAAGTTACAGGCAGCTCTGGAGCAGGCTCTG GAGAGGAAGAATGAGCTGATCTCCCAGGACTCTGACAGCGACTCCGACGATGAATGTAAT ACCCTCAATGGGCTGGTGTCGGAGGTGTTTATCCGGTTCTTTGTGGAGACCGTTGGGCAC TACTCCCTCTTTCTGACACAGAGTGAGAAGGGAGAGAGGGCCTTTCAGCGAGAGGCCTTC CGCAAATCTGTGGCCTCCAAAAGCATCCGCCGCTTTCTTGAGGTTTTTATGGAGTCTCAG ATGTTTGCTGGCTTCATCCAAGACAGGGAGCTAAGAAAGTGTCGGGCAAAGGGCCTTTTT GAGCAGCGAGTGGAGCAGTACTTAGAAGAACTCCCAGACACTGAGCAGAGTGGAATGAAT AAGTTTCTCCGAGGTTTGGGCAACAAAATGAAGTTTCTCCACAAGAAGAAT |
| Restriction Sites | Please inquire |
| ACCN | NM_139157 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_139157.2, NP_631896.1 |
| RefSeq Size | 3039 bp |
| RefSeq ORF | 2154 bp |
| Locus ID | 6764 |
| UniProt ID | P78524 |
| Domains | DENN, dDENN, uDENN |
| Gene Summary | This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2), also known as p82, lacks an in-frame exon in the coding region, as compared to variant 1. It encodes isoform 2 that is missing an internal segment, as compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215600 | ST5 (Myc-DDK-tagged)-Human suppression of tumorigenicity 5 (ST5), transcript variant 2 |
CNY 5800.00 |
|
| RC215600L3 | Lenti-ORF clone of ST5 (Myc-DDK-tagged)-Human suppression of tumorigenicity 5 (ST5), transcript variant 2 |
CNY 7700.00 |
|
| RC215600L4 | Lenti-ORF clone of ST5 (mGFP-tagged)-Human suppression of tumorigenicity 5 (ST5), transcript variant 2 |
CNY 7700.00 |
|
| RG215600 | ST5 (tGFP-tagged) - Human suppression of tumorigenicity 5 (ST5), transcript variant 2 |
CNY 6370.00 |
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