TMEM108 (NM_023943) Human Untagged Clone
CAT＃: SC321357
TMEM108 (untagged)-Human transmembrane protein 108 (TMEM108), transcript variant 1
CNY 4288.00
CNY 7220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CT124; RTLN |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_023943.1
GGAGGGAGCCGGAGCGCTTCTCCCGAGTTGGTGATAGATTGGTGGTCATCCAACATGCAG
AAATGAATGAGCAGTGAAAAGCAGCAGAGCCGATGGGTCATGAGGATGTAAGTGCGTTTG AAGGCTTCCACACCCTCTACTCCAGGACAGAATCATGAATAAACTGGAGGATAAGCAGGA CCAGATGATACCATGAAGAGAAGTTTACAGGCCCTCTATTGCCAACTGTTAAGTTTCCTG CTGATCTTGGCACTGACCGAAGCGCTGGCATTTGCCATCCAGGAACCATCTCCCAGGGAA TCTCTTCAGGTCCTCCCTTCAGGCACTCCCCCGGGAACCATGGTGACAGCACCCCACAGC TCTACCAGACATACTTCTGTGGTGATGCTGACCCCCAATCCCGATGGACCCCCCTCACAG GCTGCAGCTCCCATGGCAACACCGACACCCCGTGCAGAGGGGCACCCTCCTACGCACACC ATCTCCACCATCGCTGCGACAGTAACCGCCCCCCATTCTGAAAGCTCCCTGTCCACAGGG CCCGCTCCAGCAGCCATGGCAACCACATCCTCCAAGCCAGAGGGCCGCCCTCGAGGGCAG GCTGCCCCCACCATCCTGCTGACAAAGCCACCGGGGGCCACCAGCCGCCCCACCACAGCG CCCCCCCGCACTACCACACGCAGGCCCCCCAGGCCCCCAGGCTCTTCCCGAAAAGGGGCT GGTAATTCATCACGCCCTGTCCCGCCTGCACCTGGTGGCCACTCCAGGAGTAAAGAAGGA CAGCGAGGACGAAATCCAAGCTCCACACCTCTGGGGCAGAAGCGGCCCCTGGGGAAAATC TTTCAGATCTACAAGGGCAACTTCACAGGGTCTGTGGAACCGGAGCCCTCTACCCTCACC CCCAGGACCCCACTCTGGGGCTACTCCTCTTCACCACAGCCCCAGACAGTGGCTGCGACC ACAGTGCCCAGCAATACCTCATGGGCACCCACCACCACCTCCCTGGGGCCTGCAAAGGAC AAGCCAGGCCTTCGCAGAGCAGCCCAGGGGGGTGGTTCTACCTTCACCAGCCAAGGAGGG ACACCAGATGCCACAGCAGCCTCAGGTGCCCCTGTCAGTCCACAAGCTGCCCCAGTGCCT TCTCAGCGCCCCCACCACGGTGACCCACAGGATGGCCCCAGCCATAGTGACTCTTGGCTT ACTGTTACCCCTGGCACCAGCAGACCTCTGTCTACCAGCTCTGGGGTCTTCACGGCTGCC ACGGGGCCCACCCCAGCTGCCTTCGATACCAGTGTCTCAGCCCCTTCCCAGGGGATTCCT CAGGGAGCATCCACAACCCCACAAGCTCCAACCCATCCCTCCAGGGTCTCAGAAAGCACT ATTTCTGGAGCCAAGGAGGAGACTGTGGCCACCCTCACCATGACCGACCGGGTGCCCAGT CCTCTCTCCACAGTGGTATCCACAGCCACAGGCAATTTCCTCAACCGCCTGGTCCCCGCC GGGACCTGGAAGCCTGGGACAGCAGGGAACATCTCCCATGTGGCCGAGGGGGACAAACCG CAGCACAGAGCCACCATCTGCCTGAGCAAGATGGATATCGCCTGGGTGATCCTGGCCATC AGCGTGCCCATCTCCTCCTGCTCTGTCCTGCTGACGGTGTGCTGCATGAAGAGGAAGAAG AAGACCGCCAACCCGGAGAACAACCTGAGCTACTGGAACAACACCATCACCATGGACTAC TTCAACAGGCATGCTGTGGAGCTGCCCAGGGAGATCCAGTCCCTTGAAACCTCTGAGGAC CAGCTCTCAGAGCCCCGCTCCCCAGCCAATGGCGACTATAGAGACACTGGGATGGTCCTT GTTAACCCCTTCTGTCAAGAAACACTGTTTGTGGGAAACGATCAAGTATCTGAGATCTAA CTACAGCAGGCATCACTTTGCCATTCCGTATTTTTCGTCTCTAAATTATAAATATACAAA TATATATATTATAAATATAACCTTTGTGTAACCCTGACTTAATGAGAAACATTTTCAGCT TTTTTTCCTATGAATTGTCAACATCTTTTTTACAAGTGTGGTTTAAAAAAAAAAAAACTT TACAGAATGATCTGTGGCTTTATAAAATAAAGGTATTTCTAAGCAAAAAAAAAAAAAAAA AA |
| Restriction Sites | Please inquire |
| ACCN | NM_023943 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_023943.1, NP_076432.1 |
| RefSeq Size | 2162 bp |
| RefSeq ORF | 1728 bp |
| Locus ID | 66000 |
| UniProt ID | Q6UXF1 |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | Transmembrane protein required for proper cognitive functions. Involved in the development of dentate gyrus (DG) neuron circuitry, is neccessary for AMPA receptors surface expression and proper excitatory postsynaptic currents of DG granule neurons. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. Through the interaction with DST, mediates the docking of the dynein/dynactin motor complex to vesicle cargos for retrograde axonal transport. In hippocampal neurons, required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 and recruits the WAVE1 complex to facilitate actin-dependent BDNF:NTRK2 early endocytic trafficking and mediate signaling from early endosomes.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Both variant 1 and 2 encode the same isoform. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200953 | TMEM108 (Myc-DDK-tagged)-Human transmembrane protein 108 (TMEM108), transcript variant 1 |
CNY 4280.00 |
|
| RC200953L3 | Lenti ORF clone of Human transmembrane protein 108 (TMEM108), transcript variant 1, Myc-DDK-tagged |
CNY 6460.00 |
|
| RC200953L4 | Lenti ORF clone of Human transmembrane protein 108 (TMEM108), transcript variant 1, mGFP tagged |
CNY 6460.00 |
|
| RG200953 | TMEM108 (tGFP-tagged) - Human transmembrane protein 108 (TMEM108), transcript variant 1 |
CNY 5880.00 |
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