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MAGI3 (NM_001142782) Human Untagged Clone
CAT＃: SC326383
MAGI3 (untagged)-Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 1
CNY 28,600.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | dJ730K3.2; MAGI-3 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001142782, the custom clone sequence may differ by one or more nucleotides
ATGTCGAAGACGCTGAAGAAGAAGAAGCACTGGCTCAGCAAGGTGCAGGAGTGCGCCGTG TCCTGGGCCGGGCCCCCGGGCGACTTCGGCGCGGAGATCCGCGGTGGCGCGGAGCGTGGC GAGTTCCCCTACCTGGGGCGGCTCCGCGAGGAGCCCGGCGGGGGCACCTGCTGCGTCGTC TCGGGCAAGGCGCCCAGCCCAGGCGATGTGCTGCTGGAGGTAAACGGGACGCCTGTCAGC GGGCTCACCAACCGGGACACCCTGGCTGTCATCCGCCACTTCCGCGAGCCCATCCGTCTC AAGACTGTGAAACCAGGCAAAGTCATTAATAAAGATTTGCGGCATTACCTAAGTCTTCAG TTTCAAAAAGGATCAATTGACCACAAACTGCAGCAAGTGATCAGAGATAATCTCTACTTG AGAACCATTCCATGCACTACAAGGGCCCCCAGGGATGGAGAAGTACCAGGAGTGGATTAT AATTTCATTTCCGTTGAACAGTTCAAAGCACTGGAAGAGAGTGGAGCATTGTTAGAAAGT GGGACATATGATGGAAACTTCTATGGAACTCCCAAGCCTCCAGCAGAACCCAGCCCTTTT CAGCCAGATCCAGTTGATCAAGTCCTCTTTGATAATGAGTTTGATGCAGAATCTCAAAGA AAACGAACGACATCTGTCAGCAAGATGGAAAGAATGGATAGCTCTCTTCCTGAAGAGGAA GAAGATGAGGACAAGGAAGCTATTAATGGCAGTGGAAACGCAGAAAACAGAGAGAGGCAT TCTGAGTCATCTGACTGGATGAAGACTGTTCCAAGTTACAACCAAACAAATAGCTCCATG GACTTTAGAAATTATATGATGAGAGATGAGACTCTGGAACCACTGCCCAAAAACTGGGAA ATGGCCTACACTGACACAGGGATGATCTACTTCATTGACCACAATACCAAGACAACCACC TGGTTGGATCCTCGTCTTTGTAAGAAAGCCAAAGCCCCTGAAGACTGTGAAGATGGAGAG CTTCCTTATGGCTGGGAGAAAATAGAGGACCCTCAGTATGGGACATACTATGTTGATCAC CTTAACCAGAAAACCCAGTTTGAAAATCCAGTGGAGGAAGCCAAAAGGAAAAAGCAGTTA GGACAGGTTGAAATTGGGTCTTCAAAACCAGATATGGAAAAATCACACTTCACAAGAGAT CCATCCCAGCTTAAAGGTGTCCTTGTTCGAGCATCACTGAAAAAAAGCACAATGGGATTT GGTTTTACTATTATTGGTGGAGATAGACCTGATGAGTTCCTACAAGTGAAAAATGTGCTG AAAGATGGTCCCGCAGCTCAGGATGGGAAAATTGCACCAGGCGATGTTATTGTAGACATC AATGGCAACTGTGTCCTCGGTCACACTCATGCAGATGTTGTCCAGATGTTTCAATTGGTA CCTGTCAATCAGTATGTAAACCTCACTTTATGTCGTGGTTATCCACTTCCTGATGACAGT GAAGATCCTGTTGTGGACATTGTTGCTGCTACCCCTGTCATCAATGGACAGTCATTAACC AAGGGAGAGACTTGCATGAATCCTCAGGATTTTAAGCCAGGAGCAATGGTTCTGGAGCAG AATGGAAAATCGGGACACACTTTGACTGGTGATGGTCTCAATGGACCATCAGATGCAAGT GAGCAGAGAGTATCCATGGCATCGTCAGGCAGCTCCCAGCCTGAACTAGTGACTATCCCT TTGATTAAGGGCCCTAAAGGGTTTGGGTTTGCAATTGCTGACAGCCCTACTGGACAGAAG GTGAAAATGATACTGGATAGTCAGTGGTGTCAAGGCCTTCAGAAAGGAGATATAATTAAG GAAATATACCATCAAAATGTGCAGAATTTAACACATCTCCAAGTGGTAGAGGTGCTAAAG CAGTTTCCAGTAGGTGCTGATGTACCATTGCTTATCTTAAGAGGAGGTCCTCCTTCACCA ACCAAAACTGCCAAAATGAAAACAGATAAAAAGGAAAATGCAGGAAGTTTGGAGGCCATA AATGAGCCTATTCCTCAGCCTATGCCTTTTCCACCGAGCATTATCAGGTCAGGATCCCCA AAATTGGATCCTTCTGAGGTCTACCTGAAATCTAAGACTTTATATGAAGATAAACCACCA AACACCAAAGATTTGGATGTTTTTCTTCGAAAACAAGAGTCAGGGTTTGGCTTCAGGGTG CTAGGAGGAGATGGACCTGACCAGTCTATATATATTGGGGCTATTATTCCCCTGGGAGCA GCTGAGAAAGATGGTCGGCTCCGCGCAGCTGATGAACTAATGTGCATTGATGGAATTCCT GTTAAAGGGAAATCACACAAACAAGTCTTGGACCTCATGACAACTGCTGCTCGAAATGGC CATGTGTTACTAACTGTCAGACGGAAGATCTTCTATGGAGAAAAACAACCCGAGGACGAC AGCTCTCAGGCCTTCATTTCAACACAGAATGGATCTCCCCGCCTGAACCGGGCAGAGGTC CCAGCCAGGCCTGCACCCCAGGAGCCCTATGATGTTGTCTTGCAACGAAAAGAAAATGAA GGATTTGGCTTTGTCATCCTCACCTCCAAAAACAAACCACCTCCAGGAGTTATTCCTCAT AAAATTGGCCGAGTCATAGAAGGAAGTCCGGCTGACCGCTGTGGAAAACTGAAAGTTGGA GATCATATCTCTGCAGTGAATGGGCAGTCCATTGTTGAACTGTCTCATGATAACATTGTT CAGCTGATCAAAGATGCTGGTGTCACCGTCACACTAACGGTCATTGCTGAAGAAGAGCAT CATGGTCCACCATCAGGAACAAACTCAGCCAGGCAAAGCCCAGCCCTGCAGCACAGGCCC ATGGGACAGTCACAGGCCAACCACATACCTGGGGACAGAAGTGCCCTAGAAGGTGAAATT GGAAAAGATGTCTCCACTTCTTACAGACATTCTTGGTCAGACCACAAGCACCTTGCACAG CCTGACACCGCAGTAATTTCAGTTGTAGGCAGTCGGCACAATCAGAACCTTGGTTGTTAT CCAGTAGAGCTGGAGAGAGGCCCCCGGGGCTTTGGATTCAGCCTCCGAGGGGGGAAGGAG TACAACATGGGGCTGTTCATCCTTCGTCTTGCTGAAGATGGTCCTGCCATCAAAGATGGC AGAATTCATGTTGGTGACCAGATTGTTGAAATCAATGGGGAACCTACACAAGGAATCACA CATACTCGAGCAATTGAGCTCATTCAGGCTGGTGGAAATAAAGTTCTTCTTCTTTTGAGG CCAGGAACTGGCTTGATACCTGACCATGGTGATTGGGATATTAATAATCCTTCGTCTTCA AATGTGATTTATGATGAACAGTCACCATTACCCCCATCTTCACATTTTGCTTCCATATTT GAAGAGTCTCACGTGCCAGTAATTGAAGAATCTTTGAGAGTTCAGATATGTGAAAAGGCA GAAGAATTAAAGGACATTGTGCCTGAAAAGAAAAGCACTTTAAATGAAAATCAGCCTGAG ATAAAGCATCAGTCTCTTCTCCAGAAAAATGTGAGTAAGAGGGATCCACCCAGCAGTCAT GGGCACAGTAACAAGAAAAATCTATTAAAAGTAGAAAATGGTGTTACACGAAGAGGTAGA TCGGTTAGTCCCAAAAAGCCAGCCAGTCAACATTCAGAGGAACATTTGGATAAGATTCCT AGTCCTCTAAAAAATAACCCCAAAAGAAGACCCAGAGATCAATCCCTCAGCCCCAGCAAA GGGGAAAATAAAAGTTGTCAGGTCAGCACCAGGGCAGGCTCTGGACAAGATCAGTGCAGA AAAAGCAGAGGTCGGTCGGCCAGCCCAAAAAAGCAGCAAAAAATTGAAGGAAGCAAAGCT CCATCAAATGCTGAGGCCAAATTATTAGAGGGTAAGAGTCGAAGAATAGCAGGCTATACG GGCAGTAATGCTGAGCAGATCCCAGATGGGAAGGAAAAATCAGACGTCATCAGGAAAGAT GCAAAGCAGAATCAGTTGGAAAAAAGCAGAACAAGGTCTCCAGAGAAAAAAATCAAAAGA ATGGTTGAGAAATCTCTTCCATCCAAAATGACTAATAAGACTACAAGTAAAGAAGTATCT GAAAATGAAAAAGGAAAGAAAGTAACCACAGGAGAAACAAGTTCTAGTAACGATAAAATA GGAGAAAATGTCCAGCTATCAGAAAAGAGGCTGAAGCAAGAACCTGAAGAGAAGGTAGTT TCAAACAAAACAGAAGATCACAAAGGGAAAGAACTAGAGGCAGCTGACAAAAACAAAGAG ACTGGAAGGTTCAAACCGGAAAGCAGTTCTCCAGTTAAGAAAACACTGATAACTCCAGGG CCCTGGAAGGTTCCAAGTGGAAATAAAGTCACAGGCACTATTGGTATGGCTGAGAAACGG CAG |
| Restriction Sites | Please inquire |
| ACCN | NM_001142782 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001142782.1, NP_001136254.1 |
| RefSeq Size | 6536 bp |
| RefSeq ORF | 4446 bp |
| Locus ID | 260425 |
| UniProt ID | Q5TCQ9 |
| Protein Families | Druggable Genome |
| Protein Pathways | Tight junction |
| Gene Summary | Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longer protein (isoform 1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC227462 | MAGI3 (Myc-DDK-tagged)-Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 1 |
CNY 14,820.00 |
|
| RC227462L3 | Lenti-ORF clone of MAGI3 (Myc-DDK-tagged)-Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 1 |
CNY 16,720.00 |
|
| RC227462L4 | Lenti-ORF clone of MAGI3 (mGFP-tagged)-Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 1 |
CNY 16,720.00 |
|
| RG227462 | MAGI3 (tGFP-tagged) - Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 1 |
CNY 12,744.00 |
