NEIL1 (NM_001256552) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	FPG1; hFPG1; NEI1
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC330454 representing NM_001256552. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGGGAGGACGGGCCCGAGAGCGCCGCTCCTCCCCAAAACTAGGATTTGGAGCCTCACGTTCTCCCGC AAAACGAGCCCTGTGGGTGCCAGGCCAGGGGCGGCTCCCAGGTGTGGAGGGGGCAAGGTACGGGCGTCT GCCGTCGCTAAGTGCCCCCTTCCACTTAAGGCACACCTTCGCCTCCGATTCCGAACCGCCCGGGGACAG AGGCAAGTGGCAAAGCAGGGAGGGCGGAGGACTCTGCCACCCTCCCTCAGGATGCCTGAGGGCCCCGAG CTGCACCTGGCCAGCCAGTTTGTGAATGAGGCCTGCAGGGCGCTGGTGTTCGGCGGCTGCGTGGAGAAG TCCTCTGTCAGCCGCAACCCTGAGGTGCCCTTTGAGAGCAGTGCCTACCGCATCTCAGCTTCAGCCCGC GGCAAGGAGCTGCGCCTGATACTGAGCCCTCTGCCTGGGGCCCAGCCCCAACAGGAGCCACTGGCCCTG GTCTTCCGCTTCGGCATGTCCGGCTCTTTTCAGCTGGTGCCCCGCGAGGAGCTGCCACGCCATGCCCAC CTGCGCTTTTACACGGCCCCGCCTGGCCCCCGGCTCGCCCTATGTTTCGTGGACATCCGCCGGTTCGGC CGCTGGGACCTTGGGGGAAAGTGGCAGCCGGGCCGCGGGCCCTGTGTCTTGCAGGAGTACCAGCAGTTC AGGGAGAATGTGCTACGAAACCTAGCGGATAAGGCCTTTGACCGGCCCATCTGCGAGGCCCTCCTGGAC CAGAGGTTCTTCAATGGCATTGGCAACTATCTGCGGGCAGAGATCCTGTACCGGCTGAAGATCCCCCCC TTTGAGAAGGCCCGCTCGGTCCTGGAGGCCCTGCAGCAGCACAGGCCGAGCCCGGAGCTGACCCTGAGC CAGAAGATAAGGACCAAGCTGCAGAATCCAGACCTGCTGGAGCTATGTCACTCAGTGCCCAAGGAAGTG GTCCAGTTGGGGGGCAAAGGCTACGGGTCAGAGAGCGGGGAGGAGGACTTTGCTGCCTTTCGAGCCTGG CTGCGCTGCTATGGCATGCCAGGCATGAGCTCCCTGCAGGACCGGCATGGCCGTACCATCTGGTTCCAG GGGGATCCTGGACCGTTGGCACCCAAAGGGCGCAAGTCCCGCAAAAAGAAATCCAAGGCCACACAGCTG AGTCCTGAGGACAGAGTGGAGGACGCTTTGCCTCCAAGCAAGGCCCCTTCCAGGACACGAAGGGCAAAG AGAGACCTTCCTAAGAGGACTGCAACCCAGCGGCCTGAGGGGACCAGCCTCCAGCAGGACCCAGAAGCT CCCACAGTGCCCAAGAAGGGGAGGAGGAAGGGGCGACAGGCAGCCTCTGGCCACTGCAGACCCCGGAAG GTCAAGGCTGACATCCCATCCTTGGAACCAGAGGGGACCTCAGCCTCTTAG
Restriction Sites	SgfI-MluI
ACCN	NM_001256552
Insert Size	1431 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001256552.1
RefSeq Size	1820 bp
RefSeq ORF	1431 bp
Locus ID	79661
UniProt ID	Q96FI4
Protein Families	Druggable Genome
Protein Pathways	Base excision repair
MW	53 kDa
Gene Summary	This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] Transcript Variant: This variant (1) encodes the longer protein (isoform 1).

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