CAIN (CABIN1) (NM_001201429) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	CAIN; KB-318B8.7; PPP3IN
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC331424 representing NM_001201429. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGATTCGAATTGCAGCCTTAAATGCCAGCTCCACCATTGAGGATGATCATGAAGGAAGCTTTAAAAGT CACAAAACCCAGACAAAGGAGGCTCAGGAAGCAGAGGCTTTTGCATTGTACCACAAGGCCCTTGATCTG CAGAAACATGACCGGTTTGAGGAGTCTGCCAAAGCCTACCATGAGCTCTTGGAGGCGAGCCTGCTGCGG GAGGCAGTTTCATCCGGTGATGAGAAAGAGGGGTTGAAACACCCTGGGCTGATACTGAAATATTCCACT TATAAGAACTTGGCCCAGCTGGCAGCCCAGCGGGAGGATCTGGAGACAGCCATGGAGTTCTACTTAGAG GCAGTGATGCTGGACTCCACAGATGTCAACCTCTGGTATAAGATTGGACATGTGGCCCTGAGGCTCATC CGGATCCCCCTGGCTCGCCATGCTTTTGAGGAAGGGCTGCGGTGCAATCCTGACCACTGGCCCTGTTTG GATAACCTAATCACTGTCCTGTACACCCTCAGTGATTACACAACATGTCTGTACTTCATCTGCAAAGCT TTGGAGAAGGATTGCCGGTACAGCAAAGGGCTGGTCCTCAAGGAGAAGATTTTTGAGGAGCAGCCTTGT CTCCGGAAGGACTCTCTCAGAATGTTCCTCAAATGCTGGAAGTGCCTCGGAGAGAGCTTGCTGGCCATG TACAATCATCTCACCACCTGTGAGCCCCCACGTCCCAGCCTTGGCAAAAGGATTGATTTGTCGGACTAC CAGGACCCCAGCCAGCCTCTTGAGTCCTCCATGGTGGTGACGCCAGTTAACGTGATCCAGCCAAGCACT GTCAGCACCAACCCAGCTGTGGCTGTCGCCGAGCCTGTGGTCTCCTACACCTCTGTGGCTACAACCAGC TTCCCACTGCACAGTCCTGGTCTGTTGGAGACAGGCGCTCCTGTGGGTGATATTTCTGGGGGAGATAAA TCCAAGAAAGGGGTAAAACGGAAGAAGATTTCAGAAGAGAGTGGAGAAACAGCAAAGCGGCGGTCTGCC CGTGTCCGAAACACCAAGTGCAAAAAAGAAGAGAAAGTAGACTTCCAGGAGCTTCTGATGAAGTTCTTG CCGTCCAGGTTAAGAAAGCTGGACCCTGAGGAGGAAGATGATTCCTTTAATAACTATGAAGTCCAGTCA GAAGCCAAACTGGAAAGCTTCCCAAGCATTGGGCCTCAAAGGCTGTCATTTGACTCAGCCACATTCATG GAATCTGAAAAGCAGGACGTGCATGAGTTCCTGCTGGAGAACCTAACCAACGGGGGCATCCTGGAGCTG ATGATGCGCTACCTGAAAGCCATGGGCCACAAGTTCTTGGTAAGGTGGCCTCCAGGCTTGGCGGAGGTC GTGCTCAGCGTCTACCACAGCTGGAGGAGGCACAGCACCAGCCTGCCCAACCCGCTGCTGAGGGACTGC AGCAACAAGCACATCAAGGACATGATGCTGATGTCTCTCTCCTGCATGGAACTCCAGCTGGACCAGTGG CTGCTGACCAAAGGCAGAAGCTCTGCAGTGTCTCCTCGGAACTGCCCTGCTGGTATGGTGAATGGCAGA TTTGGACCTGACTTCCCAGGGACCCACTGCCTGGGTGACCTCCTACAGCTGTCATTTGCCTCGTCCCAG CGCGACCTGTTCGAGGATGGTTGGCTGGAGTTTGTGGTCCGTGTTTACTGGCTGAAGGCTCGCTTCCTG GCGCTGCAGGGAGACATGGAGCAGGCCCTGGAGAACTATGACATCTGCACAGAAATGCTCCAGAGTTCC ACCGCCATCCAGGTGGAGGCAGGGGCTGAACGAAGAGACATTGTCATCCGGCTGCCCAACCTCCATAAT GACTCTGTGGTTTCCCTGGAGGAGATTGATAAGAACCTGAAGTCGCTGGAGCGGTGCCAGTCCCTGGAG GAGATTCAGCGGCTGTATGAAGCAGGCGACTACAAGGCTGTTGTGCATCTGCTCCGCCCCACTTTGTGC ACCAGTGGGTTTGACCGGGCCAAACACCTGGAGTTTATGACTTCCATTCCTGAGAGGCCAGCCCAGCTG CTTCTTCTGCAGGACTCCTTGCTCCGGCTGAAGGACTATCGGCAGTGTTTTGAGTGTTCCGATGTGGCT CTGAACGAGGCTGTCCAGCAGATGGTGAACTCAGGTGAGGCTGCCGCCAAGGAGGAGTGGGTGGCCACA GTGACCCAACTGCTGATGGGCATCGAGCAGGCCCTCTCTGCGGACAGCAGTGGTAGCATCCTGAAGGTA TCATCCTCCACCACTGGCCTTGTGCGGCTCACCAACAACCTCATCCAGGTCATTGACTGCAGCATGGCT GTGCAGGAGGAGGCCAAGGAGCCCCACGTCTCTTCAGTGCTACCCTGGATCATTCTACACCGGATCATC TGGCAGGAGGAAGACACCTTCCATTCTCTGTGCCACCAGCAGCAGCTCCAAAACCCAGCGGAGGAAGGG ATGTCAGAGACGCCCATGCTCCCATCCTCCCTCATGCTGCTGAACACAGCCCACGAGTATTTGGGCAGA AGGTCCTGGTGCTGCAATTCAGATGGGGCTCTGCTGCGATTCTATGTGCGAGTACTCCAGAAGGAACTG GCTGCATCCACCTCTGAAGACACGCACCCTTACAAGGAGGAGCTGGAGACAGCCTTGGAGCAGTGCTTC TACTGCCTGTACAGCTTCCCCAGCAAGAAGAGTAAGGCCAGGTACCTGGAGGAACACTCGGCCCAGCAG GTGGATCTTATATGGGAGGATGCACTGTTCATGTTTGAGTATTTTAAGCCCAAGACCCTTCCTGAATTT GACAGCTATAAGACCAGCACCGTGTCTGCTGACTTGGCCAACCTACTGAAGAGAATTGCCACCATTGTG CCTCGCACAGAGAGGCCAGCCCTTAGCCTGGACAAAGTCTCTGCCTACATTGAGGGAACTTCAACTGAG GTACCCTGCCTCCCAGAGGGGGCTGACCCCTCCCCTCCAGTGGTGAACGAGCTTTACTACCTCCTGGCT GATTATCATTTCAAAAACAAGGAGCAGTCCAAGGCCATCAAGTTCTACATGCATGACATCTGCATCTGC CCCAATAGGTTTGATTCCTGGGCAGGCATGGCTCTGGCCCGGGCCAGCCGCATTCAGGACAAGCTGAAC TCCAATGAGCTGAAGAGTGATGGGCCCATTTGGAAGCATGCCACGCCCGTCTTGAACTGCTTCCGTCGG GCCCTGGAGATTGACAGCTCCAACTTGTCCCTATGGATTGAGTATGGCACCATGTCCTATGCCTTGCAC TCATTCGCCTCACGTCAATTGAAGCAGTGGAGAGGCGAGCTGCCCCCTGAGCTCGTGCAGCAGATGGAG GGCCGGCGCGACAGCATGCTAGAGACAGCCAAGCACTGTTTCACATCAGCAGCCCGCTGCGAGGGTGAT GGTGACGAGGAGGAGTGGCTCATCCACTACATGCTGGGCAAGGTGGCTGAGAAGCAGCAGCAGCCACCC ACCGTTTACTTGCTGCACTACAGGCAGGCTGGCCACTACCTGCACGAGGAGGCTGCCCGCTACCCCAAG AAGATCCACTACCACAACCCACCTGAGCTGGCCATGGAGGCCCTGGAGGTGTACTTTCGGCTCCATGCT TCCATCCTGAAGCTCCTGGGGAAGCCCGATTCTGGGGTTGGTGCAGAGGTCCTGGTCAACTTTATGAAG GAGGCTGCAGAAGGACCCTTTGCCAGGGGCGAGGAGAAGAACACACCCAAAGCTTCAGAAAAGGAGAAG GCCTGCCTGGTGGACGAGGACTCCCACTCTTCAGCTGGGACACTGCCGGGCCCCGGAGCCTCCCTCCCC TCCTCCTCTGGCCCAGGTCTGACATCCCCACCTTACACAGCCACTCCGATTGACCACGATTACGTCAAA TGTAAAAAACCCCACCAGCAGGCAACGCCGGACGACCGAAGCCAGGACAGCACAGCCGTAGCACTCTCA GACTCTAGCTCAACGCAGGACTTCTTTAATGAGCCCACCAGCTTACTGGAAGGCTCCAGGAAATCCTAC ACAGAGAAGAGGCTGCCCATTCTCAGTTCCCAAGCAGGAGCGACGGGTAAAGATCTTCAGGGGGCCACA GAAGAAAGAGGAAAAAACGAGGAGTCATTGGAGAGTACAGAAGGCTTCCGGGCTGCAGAGCAAGGTGTC CAGAAGCCTGCTGCAGAAACCCCAGCCTCTGCTTGCATCCCTGGCAAGCCCTCAGCATCCACACCCACC CTGTGGGATGGGAAGAAGAGAGGGGACCTCCCAGGGGAGCCAGTGGCCTTCCCCCAGGGGCTGCCGGCT GGTGCTGAGGAGCAGCGGCAGTTTCTCACAGAGCAGTGCATCGCCTCCTTCCGCCTGTGCCTGAGCCGC TTCCCCCAGCACTATAAGAGTCTCTACCGTCTGGCCTTCCTCTACACCTACAGCAAGACCCACCGGAAC CTCCAGTGGGCCCGCGACGTGTTGCTAGGCAGCAGTATCCCGTGGCAACAACTGCAGCACATGCCGGCA CAGGGGCTCTTCTGCGAGAGGAACAAGACCAATTTCTTCAACGGCATCTGGCGGATCCCCGTGGACGAG ATTGACCGGCCGGGCAGCTTTGCCTGGCACATGAACCGCTCCATCGTGCTGCTGCTCAAGGTGCTGGCC CAGCTGCGGGACCACAGCACCCTGCTGAAGGTGTCCTCCATGCTTCAGCGGACCCCAGACCAGGGCAAG AAGTATCTGCGAGATGCTGACCGCCAGGTCCTGGCGCAGCGGGCCTTCATCCTCACTGTGAAGGTGCTC GAAGACACGCTGAGCGAGCTCGCAGAGGGGTCAGAACGCCCAGGGCCCAAGGTCTGTGGCCTCCCCGGA GCCAGGATGACCACCGATGTCTCACACAAGGCCAGTCCTGAGGATGGCCAGGAGGGCCTCCCCCAGCCG AAGAAGCCCCCTCTGGCTGATGGCTCAGGGCCAGGGCCCGAGCCAGGAGGCAAAGTGGGCCTCCTCAAC CACCGGCCTGTGGCCATGGATGCAGGAGACAGTGCAGACCAAAGCGGGGAGCGGAAGGATAAAGAGAGC CCACGGGCAGGGCCCACTGAGCCCATGGACACGAGTGAGGCCACTGTTTGCCACTCAGACTTGGAGCGG ACACCACCCCTGCTGCCAGGTCGCCCCGCAAGGGACCGGGGCCCCGAGAGCCGGCCCACTGAGCTGTCC CTGGAGGAGCTGAGCATCAGTGCCCGGCAGCAGCCCACCCCGCTCACCCCAGCCCAGCCAGCCCCCGCC CCCGCCCCCGCCACCACCACAGGGACCAGGGCAGGGGGCCACCCGGAGGAGCCGCTCTCCCGGCTCAGC CGCAAGAGGAAGCTCCTGGAGGACACAGAGTCAGGCAAGACACTTCTGTTGGATGCCTACCGTGTGTGG CAGCAGGGCCAGAAGGGTGTGGCCTATGACCTGGGCCGTGTGGAGAGGATCATGTCGGAGACCTACATG CTCATCAAGCAGGTGGATGAGGAGGCTGCGCTGGAGCAGGCTGTGAAGTTCTGCCAGGTCCATCTTGGG GCTGCCGCCCAGAGACAGGCCTCGGGGGACACCCCCACCACTCCAAAGCACCCCAAAGACAGCCGAGAG AACTTCTTTCCTGTGACAGTGGTGCCCACAGCCCCTGACCCTGTGCCAGCTGACTCTGTCCAGCGGCCC AGTGATGCTCACACCAAGCCTCGCCCTGCACTAGCTGCCGCCACAACTATTATCACCTGCCCTCCGTCA GCATCAGCTTCCACCCTGGACCAGTCCAAGGACCCTGGGCCTCCCCGGCCACACAGGCCTGAAGCTACC CCCAGCATGGCCTCTCTGGGCCCAGAGGGAGAAGAGCTGGCGAGAGTGGCAGAGGGCACCAGCTTCCCG CCTCAGGAGCCACGGCACAGTCCGCAGGTGAAGATGGCCCCCACAAGTTCCCCGGCAGAGCCACACTGC TGGCCGGCAGAGGCTGCCCTGGGCACAGGCGCTGAGCCCACCTGCAGCCAGGAGGGGAAACTGAGGCCT GAGCCGAGAAGGGATGGGGAGGCTCAGGAGGCTGCGAGTGAGACTCAGCCCCTGAGCTCTCCCCCAACA GCTGCCAGCTCCAAGGCCCCCAGCAGTGGGAGTGCCCAGCCACCAGAGGGTCACCCAGGCAAGCCTGAG CCCAGCCGGGCTAAGTCCCGCCCCCTGCCCAACATGCCAAAGCTGGTCATCCCCTCCGCCGCCACCAAG TTCCCCCCTGAGATCACCGTCACGCCACCCACCCCAACCCTGCTCTCCCCCAAAGGCAGCATCTCGGAG GAGACCAAGCAGAAGCTGAAGTCAGCCATCCTTTCTGCCCAGTCTGCTGCCAACGTGAGGAAGGAGAGC CTATGCCAGCCAGCCCTGGAGGTCCTGGAGACATCCAGCCAGGAGTCCTCGCTGGAGAGCGAGACAGAC GAGGACGACGACTACATGGACATTTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001201429
Insert Size	6513 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001201429.1
RefSeq Size	7072 bp
RefSeq ORF	6513 bp
Locus ID	23523
UniProt ID	Q9Y6J0
Protein Families	Druggable Genome
MW	240.8 kDa
Gene Summary	Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. [provided by RefSeq, Jan 2011] Transcript Variant: This variant (3) differs in the 5' UTR and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.

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