MEGF10 (NM_001256545) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	EMARDD; SR-F3
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC332415 representing NM_001256545. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGTTATTTCTTTGAACTCATGCCTGAGCTTTATTTGTTTATTGTTATGCCACTGGATTGGGACAGCA TCACCTCTGAATCTTGAAGACCCTAATGTGTGTAGCCACTGGGAAAGCTACTCAGTGACTGTGCAAGAG TCATACCCACATCCCTTTGATCAAATTTACTACACGAGCTGCACTGACATTCTAAACTGGTTTAAATGC ACGCGGCACAGAGTCAGCTATCGGACAGCCTATCGACATGGGGAGAAGACTATGTATAGGCGCAAGTCT CAGTGTTGTCCTGGATTTTATGAAAGCGGGGAAATGTGTGTCCCCCACTGTGCTGATAAATGTGTCCAT GGTCGCTGTATTGCTCCAAACACCTGTCAGTGTGAGCCTGGCTGGGGAGGGACCAACTGCTCCAGTGCC TGCGATGGTGATCACTGGGGTCCCCACTGCACCAGCCGGTGCCAGTGCAAAAATGGGGCTCTGTGCAAC CCCATCACCGGGGCTTGCCACTGTGCTGCGGGCTTCCGGGGCTGGCGCTGCGAGGACCGCTGTGAGCAG GGCACCTATGGTAACGACTGTCATCAGAGATGCCAGTGCCAGAATGGAGCCACCTGCGACCACGTCACG GGGGAATGCCGCTGCCCACCAGGATACACCGGAGCCTTCTGTGAGGATCTTTGTCCTCCTGGTAAACAT GGTCCACAGTGTGAGCAGAGATGCCCTTGTCAAAATGGAGGAGTGTGTCATCACGTCACTGGAGAATGC TCTTGCCCTTCTGGCTGGATGGGCACAGTGTGTGGTCAGCCTTGCCCCGAGGGTCGCTTTGGAAAGAAC TGTTCCCAAGAATGCCAGTGCCATAATGGAGGGACGTGTGATGCTGCCACAGGCCAATGTCATTGCAGT CCAGGATACACAGGGGAACGGTGCCAGGATGAGTGTCCTGTTGGGACCTATGGCGTTCTCTGTGCTGAG ACCTGCCAGTGTGTCAACGGAGGGAAGTGTTACCACGTGAGCGGCGCATGCCTCTGTGAAGCAGGCTTT GCTGGCGAGCGCTGCGAAGCACGCCTGTGTCCTGAGGGGCTCTACGGCATCAAATGTGACAAACGGTGT CCCTGCCACCTGGAAAACACTCATAGCTGTCACCCCATGTCTGGAGAGTGTGCCTGCAAGCCGGGCTGG TCAGGACTCTACTGTAATGAGACATGTTCTCCTGGATTCTACGGGGAAGCTTGCCAGCAGATCTGCAGC TGCCAAAATGGGGCAGACTGTGACAGTGTGACTGGAAAGTGCACCTGTGCCCCAGGATTCAAAGGAATT GACTGCTCTACCCCATGCCCTCTGGGAACCTATGGGATAAACTGTTCCTCTCGCTGTGGCTGTAAAAAT GATGCAGTCTGCTCTCCTGTGGACGGGTCTTGTACTTGCAAGGCAGGCTGGCACGGGGTGGACTGCTCC ATCAGATGTCCCAGTGGCACATGGGGCTTTGGCTGTAACTTAACATGCCAGTGCCTCAACGGGGGAGCC TGCAACACCCTGGACGGGACCTGCACGTGTGCACCTGGATGGCGCGGGGAGAAATGCGAACTTCCCTGC CAGGATGGCACGTACGGGCTGAACTGTGCTGAGCGCTGCGACTGCAGCCACGCAGATGGCTGCCACCCT ACCACGGGCCATTGCCGCTGCCTCCCCGGATGGTCAGGTGTCCACTGTGACAGCGTGTGTGCTGAGGGA CGCTGGGGCCCCAACTGCTCCCTGCCCTGCTACTGTAAAAATGGGGCTTCATGCTCCCCTGATGATGGC ATCTGCGAGTGTGCACCAGGCTTCCGAGGCACCACTTGTCAGAGGATCTGCTCCCCTGGTTTTTATGGG CATCGCTGCAGCCAGACATGCCCACAGTGCGTTCACAGCAGCGGGCCCTGCCACCACATCACCGGCCTG TGTGACTGCTTGCCTGGCTTCACAGGCGCCCTCTGCAATGAAGTGTGTCCCAGTGGCAGATTTGGGAAA AACTGTGCAGGAATTTGTACCTGCACCAACAACGGAACCTGTAACCCCATTGACAGATCTTGTCAGTGT TACCCCGGTTGGATTGGCAGTGACTGCTCTCAACCATGTCCACCTGCCCACTGGGGCCCAAACTGCATC CACACGTGCAACTGCCATAATGGAGCTTTCTGCAGCGCCTACGATGGGGAATGTAAATGCACTCCTGGC TGGACAGGGCTCTACTGCACTCAGAGATGTCCTCTAGGGTTTTATGGAAAAGATTGTGCACTGATATGC CAATGTCAAAACGGAGCTGACTGCGACCACATTTCTGGGCAGTGTACTTGCCGCACTGGATTCATGGGA CGGCACTGTGAGCAGAAGTGCCCTTCAGGAACATATGGCTATGGCTGTCGCCAGATATGTGATTGTCTG AACAACTCCACCTGCGACCACATCACTGGGACCTGTTACTGCAGCCCCGGATGGAAGGGAGCGAGATGT GATCAAGCTGGTGTTATCATAGTTGGAAATCTGAACAGCTTAAGCCGAACCAGTACTGCTCTCCCTGCT GATTCCTACCAGATCGGGGCCATTGCAGGCATCATCATTCTTGTCCTAGTTGTTCTCTTCCTACTGGCA TTGTTCATTATTTATAGACACAAGCAGAAGGGAAAGGAATCAAGCATGCCAGCAGTTACCTACACCCCT GCTATGAGGGTCGTCAATGCAGATTATACCATTTCAGGAACCCTTCCTCACAGCAATGGTGGAAACGCT AATAGCCACTACTTCACCAATCCCAGTTACCACACGCTCACCCAGTGTGCCACATCCCCTCACGTCAAC AACAGGGACAGGATGACTGTCACGAAGTCAAAAAACAATCAACTGTTTGTGAATCTTAAAAATGTGAAC CCTGGGAAGAGAGGCCCTGTGGGGGACTGCACTGGGACATTGCCGGCTGACTGGAAACATGGCGGCTAC CTCAACGAGCTCGGTGCTTTTGGACTTGACAGAAGCTATATGGGAAAATCCTTAAAAGACCTGGGAAAG AATTCTGAATATAATTCAAGTAACTGCTCCCTAAGCAGTTCTGAGAACCCATATGCCACTATTAAAGAC CCACCTGTACTTATCCCGAAAAGCTCAGAGTGTGGTTATGTGGAGATGAAATCGCCGGCACGAAGAGAT TCCCCATATGCAGAGATCAATAACTCAACTTCAGCCAACAGGAATGTCTATGAAGTTGAACCTACAGTG AGTGTTGTCCAAGGAGTATTCAGCAATAATGGGCGTCTCTCCCAGGATCCATATGACCTCCCAAAGAAC AGTCACATCCCTTGTCATTATGACCTGCTGCCAGTCCGAGACAGTTCATCCTCCCCTAAGCAAGAGGAC AGTGGTGGTAGCAGCAGCAACAGCAGCAGCAGCAGTGAATGA
Restriction Sites	SgfI-MluI
ACCN	NM_001256545
Insert Size	3423 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001256545.1
RefSeq Size	7638 bp
RefSeq ORF	3423 bp
Locus ID	84466
UniProt ID	Q96KG7
Protein Families	Transmembrane
MW	122.2 kDa
Gene Summary	This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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