Apolipoprotein L 1 (APOL1) (NM_145343) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC217000L3V
- LentiORF®
Lenti ORF particles, APOL1 (Myc-DDK tagged) - Human apolipoprotein L, 1 (APOL1), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 8,550.00
Cited in 4 publications. |
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CNY 2,950.00
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Specifications
Product Data | |
Product Name | Apolipoprotein L 1 (APOL1) (NM_145343) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | APO-L; APOL; APOL-I; FSGS4 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_145343 |
ORF Size | 1242 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC217000).
|
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_145343.1, NP_663318.1 |
RefSeq Size | 3010 bp |
RefSeq ORF | 1245 bp |
Locus ID | 8542 |
Protein Families | Secreted Protein, Transmembrane |
MW | 41.1 kDa |
Gene Summary | This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008] |
Citations (4)
The use of this cDNA Clones has been cited in the following citations: |
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Endoplasmic reticulum-translocation is essential for APOL1 cellular toxicity
,null,
iScience
,PubMed ID 35072009
[APOL1]
|
Blocking the 5′ splice site of exon 4 by a morpholino oligomer triggers APOL1 protein isoform switch
,null,
Scientific Reports
,PubMed ID 29880816
[APOL1]
|
APOL1-G1 in Nephrocytes Induces Hypertrophy and Accelerates Cell Death
,null,
Journal of the American Society of Nephrology : JASN
,PubMed ID 27864430
[APOL1]
|
Exon 4-encoded sequence is a major determinant of cytotoxicity of apolipoprotein L1
,null,
American Journal of Physiology - Cell Physiology
,PubMed ID 25924622
[APOL1]
|
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