United States
Germany
Japan
United Kingdom
China
LRP6 (NM_002336) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC218918L3V
- LentiORF®
-
Lenti ORF particles, LRP6 (Myc-DDK tagged) - Human low density lipoprotein receptor-related protein 6 (LRP6), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 11,210.00
货期*
详询
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Product Name | LRP6 (NM_002336) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | ADCAD2; STHAG7 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_002336 |
| ORF Size | 4839 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC218918).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_002336.1, NP_002327.1 |
| RefSeq Size | 5301 bp |
| RefSeq ORF | 4842 bp |
| Locus ID | 4040 |
| Domains | ldl_recept_b, ldl_recept_a, EGF, EGF |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Wnt signaling pathway |
| MW | 180.44 kDa |
| Gene Summary | This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
