Human MRF (MYRF) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MYRF
Locus ID	745
Kit Components	GA100518G1, MRF gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100518G2, MRF gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100518G3, MRF gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001127392, NM_013279
Synonyms	C11orf9; MRF; Ndt80; pqn-47
Summary	This gene encodes a transcription factor that is required for central nervous system myelination and may regulate oligodendrocyte differentiation. It is thought to act by increasing the expression of genes that effect myelin production but may also directly promote myelin gene expression. Loss of a similar gene in mouse models results in severe demyelination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

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