Human IGF1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IGF1
Locus ID	3479
Kit Components	GA102348G1, IGF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102348G2, IGF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102348G3, IGF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000618, NM_001111283, NM_001111284, NM_001111285
Synonyms	IGF-I; IGFI; MGF
Summary	The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]

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