Human PCM1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PCM1
Locus ID	5108
Kit Components	GA103416G1, PCM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103416G2, PCM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103416G3, PCM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001315507, NM_001315508, NM_006197, NM_001352632, NM_001352633, NM_001352634, NM_001352635, NM_001352636, NM_001352637, NM_001352638, NM_001352639, NM_001352640, NM_001352641, NM_001352642, NM_001352643, NM_001352644, NM_001352645, NM_001352646, NM_001352647, NM_001352648, NM_001352649, NM_001352650, NM_001352651, NM_001352652, NM_001352653, NM_001352654, NM_001352655, NM_001352656, NM_001352657, NM_001352658, NM_001352659, NM_001352660, NR_148032
Synonyms	PTC4
Summary	The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

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