Human PRPS1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PRPS1
Locus ID	5631
Kit Components	GA103816G1, PRPS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103816G2, PRPS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103816G3, PRPS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001204402, NM_002764
Synonyms	ARTS; CMTX5; DFN2; DFNX1; PPRibP; PRS-I; PRSI
Summary	This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

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