Human TFIISH (TCEA3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TCEA3
Locus ID	6920
Kit Components	GA104774G1, TFIISH gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104774G2, TFIISH gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104774G3, TFIISH gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003196
Synonyms	TFIIS; TFIIS.H
Summary	Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.[UniProtKB/Swiss-Prot Function]

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