Human 14-3-3 zeta (YWHAZ) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	YWHAZ
Locus ID	7534
Kit Components	GA105185G1, 14-3-3 zeta gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105185G2, 14-3-3 zeta gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105185G3, 14-3-3 zeta gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001135699, NM_001135700, NM_001135701, NM_001135702, NM_003406, NM_145690
Synonyms	14-3-3-zeta; HEL-S-3; HEL4; KCIP-1; YWHAD
Summary	This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008]

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