Human CAPS1 (CADPS) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CADPS
Locus ID	8618
Kit Components	GA105705G1, CAPS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105705G2, CAPS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105705G3, CAPS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003716, NM_183393, NM_183394
Synonyms	CADPS1; CAPS; CAPS1; UNC-31
Summary	This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq, Aug 2008]

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