Human RABEP1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RABEP1
Locus ID	9135
Kit Components	GA106088G1, RABEP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106088G2, RABEP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106088G3, RABEP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001083585, NM_001291581, NM_001291582, NM_004703
Synonyms	RAB5EP; RABPT5
Summary	Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane (PubMed:22841712). Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium (By similarity).[UniProtKB/Swiss-Prot Function]

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