Human IER2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IER2
Locus ID	9592
Kit Components	GA106425G1, IER2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106425G2, IER2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106425G3, IER2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_004907
Synonyms	ETR101
Summary	DNA-binding protein that seems to act as a transcription factor (PubMed:19584537). Involved in the regulation of neuronal differentiation, acts upon JNK-signaling pathway activation and plays a role in neurite outgrowth in hippocampal cells (By similarity). May mediate with FIBP FGF-signaling in the establishment of laterality in the embryo (By similarity). Promotes cell motility, seems to stimulate tumor metastasis (PubMed:22120713).[UniProtKB/Swiss-Prot Function]

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