Human GCAP3 (GUCA1C) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GUCA1C
Locus ID	9626
Kit Components	GA106446G1, GCAP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106446G2, GCAP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106446G3, GCAP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_005459, NM_001363884
Synonyms	GCAP3
Summary	Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.[UniProtKB/Swiss-Prot Function]

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