Human IQ motif containing B1 (IQCB1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IQCB1
Locus ID	9657
Kit Components	GA106474G1, IQ motif containing B1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106474G2, IQ motif containing B1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106474G3, IQ motif containing B1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001023570, NM_001023571, NM_001319107, NM_014642, NR_134968
Synonyms	NPHP5; PIQ; SLSN5
Summary	This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Jan 2016]

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