Human SPG48 (AP5Z1) activation kit by CRISPRa
CAT#: GA106693
AP5Z1 CRISPRa kit - CRISPR gene activation of human adaptor related protein complex 5 subunit zeta 1
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | AP5Z1 |
Locus ID | 9907 |
Kit Components | GA106693G1, SPG48 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106693G2, SPG48 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106693G3, SPG48 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_014855, NM_001364858, NR_157345 |
Synonyms | KIAA0415; SPG48; zeta |
Summary | This gene was identified by genome-wide screen for genes involved in homologous recombination DNA double-strand break repair (HR-DSBR). The encoded protein was found in a complex with other proteins that have a role in HR-DSBR. Knockdown of this gene reduced homologous recombination, and mutations in this gene were found in patients with spastic paraplegia. It was concluded that this gene likely encodes a helicase (PMID:20613862). [provided by RefSeq, Jan 2011] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN421565 | AP5Z1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |