Human BIG1 (ARFGEF1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARFGEF1
Locus ID	10565
Kit Components	GA107225G1, BIG1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107225G2, BIG1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107225G3, BIG1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006421
Synonyms	ARFGEP1; BIG1; P200
Summary	ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP. It contains a Sec7 domain, which may be responsible for guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Aug 2011]

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