Human PPM1E activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PPM1E
Locus ID	22843
Kit Components	GA107846G1, PPM1E gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107846G2, PPM1E gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107846G3, PPM1E gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_014906, NR_048561
Synonyms	caMKN; CaMKP-N; POPX1; PP2CH
Summary	This gene encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5'-AMP-activated protein kinase (AMPK) and the multifunctional calcium/calmodulin-dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]

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