Human RIM1 (RIMS1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RIMS1
Locus ID	22999
Kit Components	GA107960G1, RIM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107960G2, RIM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107960G3, RIM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001168407, NM_001168408, NM_001168409, NM_001168410, NM_001168411, NM_014989, NM_001350411, NM_001350412, NM_001350413, NM_001350414, NM_001350415, NM_001350416, NM_001350417, NM_001350418, NM_001350419, NM_001350420, NM_001350421, NM_001350422, NM_001350423, NM_001350424, NM_001350425, NM_001350426, NM_001350427, NM_001350428, NM_001350429, NM_001350430, NM_001350431, NM_001350432, NM_001350433, NM_001350434, NM_001350435, NM_001350436, NM_001350437, NM_001350438, NM_001350439, NM_001350440, NM_001350441, NM_001350442, NM_001350443, NM_001350444, NM_001350445, NM_001350446, NM_001350447, NM_001350448, NM_001350449, NM_001350450, NM_001350452, NM_001350454, NM_001350455, NM_001350456, NM_001350457, NM_001350458, NM_001350459, NM_001350460, NM_001350461, NM_001350462, NM_001350463, NM_001350464, NM_001350465, NM_001350466, NM_001350467, NM_001350468, NM_001350469, NM_001350470, NM_001350471, NM_001350472, NM_001350473, NM_001350474
Synonyms	CORD7; RAB3IP2; RIM; RIM1
Summary	The protein encoded by this gene is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. This gene also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]

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