Human LARG (ARHGEF12) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGEF12
Locus ID	23365
Kit Components	GA108252G1, LARG gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108252G2, LARG gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108252G3, LARG gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001198665, NM_001301084, NM_015313
Synonyms	LARG; PRO2792
Summary	Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

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