Human HA1 (ARHGAP45) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGAP45
Locus ID	23526
Kit Components	GA108369G1, HA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108369G2, HA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108369G3, HA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001258328, NM_001282334, NM_001282335, NM_001321232, NM_012292, NR_047652
Synonyms	HA-1; HLA-HA1; HMHA1
Summary	Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR-domin which is able to play an autoinhibitory effect on this RhoGAP activity.[UniProtKB/Swiss-Prot Function]

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