Human DPS1 (PDSS1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PDSS1
Locus ID	23590
Kit Components	GA108419G1, DPS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108419G2, DPS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108419G3, DPS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_014317, NM_001321978, NM_001321979
Synonyms	COQ1; COQ10D2; DPS; hDPS1; SPS; TPRT; TPT; TPT 1
Summary	The protein encoded by this gene is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of coenzyme Q10 deficiency. [provided by RefSeq, Jul 2008]

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