Human CEMIP2 activation kit by CRISPRa

CAT#: GA108468

CEMIP2 CRISPRa kit - CRISPR gene activation of human cell migration inducing hyaluronidase 2



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CNY 12255.00


货期*
4周

规格
    • 1 kit

Product images

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CEMIP2
Locus ID 23670
Kit Components

GA108468G1, CEMIP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108468G2, CEMIP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108468G3, CEMIP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_001135820, NM_013390, NM_001349784
Synonyms OTTHUMP00000021450; transmembrane protein 2
Summary This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss. [provided by RefSeq, Mar 2017]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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