Human NFU1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NFU1
Locus ID	27247
Kit Components	GA109083G1, NFU1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109083G2, NFU1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109083G3, NFU1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001002755, NM_001002756, NM_001002757, NM_015700, NR_045631, NR_045632
Synonyms	CGI-33; HIRIP; HIRIP5; MMDS1; Nfu; NifU; NIFUC
Summary	This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

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