Human ERLEC1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ERLEC1
Locus ID	27248
Kit Components	GA109084G1, ERLEC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109084G2, ERLEC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109084G3, ERLEC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001127397, NM_001127398, NM_015701
Synonyms	C2orf30; CIM; CL24936; CL25084; HEL117; XTP3-B; XTP3TPB
Summary	This gene encodes a resident endoplasmic reticulum (ER) protein that functions in N-glycan recognition. This protein is thought to be involved in ER-associated degradation via its interaction with the membrane-associated ubiquitin ligase complex. It also functions as a regulator of multiple cellular stress-response pathways in a manner that promotes metastatic cell survival. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 21. [provided by RefSeq, Aug 2011]

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