Human ANGPTL3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ANGPTL3
Locus ID	27329
Kit Components	GA109123G1, ANGPTL3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109123G2, ANGPTL3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109123G3, ANGPTL3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_014495
Synonyms	ANG-5; ANGPT5; ANL3; FHBL2
Summary	This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Aug 2015]

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