Human C1GALT1C1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	C1GALT1C1
Locus ID	29071
Kit Components	GA109211G1, C1GALT1C1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109211G2, C1GALT1C1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109211G3, C1GALT1C1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001011551, NM_014158, NM_152692
Synonyms	C1GALT2; C38H2-L1; COSMC; HSPC067; MST143; TNPS
Summary	This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2009]

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