Human Retinol Saturase (RETSAT) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RETSAT
Locus ID	54884
Kit Components	GA110341G1, Retinol Saturase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110341G2, Retinol Saturase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110341G3, Retinol Saturase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_017750
Synonyms	FLJ20296
Summary	Catalyzes the saturation of all-trans-retinol to all-trans-13,14-dihydroretinol. Does not exhibit any activity toward all-trans-retinoic acid, nor 9-cis, 11-cis or 13-cis-retinol isomers. May play a role in the metabolism of vitamin A. Independently of retinol conversion, may regulate liver metabolism upstream of MLXIPL/ChREBP. May play a role in adipocyte differentiation.[UniProtKB/Swiss-Prot Function]

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