Human DYNC2I1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DYNC2I1
Locus ID	55112
Kit Components	GA110524G1, DYNC2I1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110524G2, DYNC2I1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110524G3, DYNC2I1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_018051, NM_001350914, NM_001350915, NM_001350916, NM_001350917, NM_001350918
Synonyms	FAP163; SRPS6; SRTD8
Summary	This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) and may facilitate the formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein contains four WD repeats and may play a role in the formation of cilia. Mutations in this gene have been associated with short-rib polydactyly and Jeune syndromes. [provided by RefSeq, Mar 2014]

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