Human C20orf31 (EDEM2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EDEM2
Locus ID	55741
Kit Components	GA110928G1, C20orf31 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110928G2, C20orf31 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110928G3, C20orf31 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001145025, NM_018217, NR_026728
Synonyms	bA4204.1; C20orf31; C20orf49
Summary	In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).[supplied by OMIM, Mar 2008]

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