Human Leukotriene B4 Receptor 2 (LTB4R2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LTB4R2
Locus ID	56413
Kit Components	GA111187G1, Leukotriene B4 Receptor 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111187G2, Leukotriene B4 Receptor 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111187G3, Leukotriene B4 Receptor 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001164692, NM_001164693, NM_019839
Synonyms	BLT2; BLTR2; JULF2; KPG_004; LTB4-R 2; LTB4-R2; NOP9
Summary	Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.[UniProtKB/Swiss-Prot Function]

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