Human Claspin (CLSPN) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CLSPN
Locus ID	63967
Kit Components	GA111937G1, Claspin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111937G2, Claspin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111937G3, Claspin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001190481, NM_022111, NM_001330490
Synonyms	MGC131612; MGC131613; MGC131615
Summary	The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

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