Human DYNC2H1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DYNC2H1
Locus ID	79659
Kit Components	GA112526G1, DYNC2H1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112526G2, DYNC2H1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112526G3, DYNC2H1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001080463, NM_001377, NM_024606
Synonyms	ATD3; DHC1b; DHC2; DNCH2; DYH1B; hdhc11; SRPS2B; SRTD3
Summary	This gene encodes a large cytoplasmic dynein protein that is involved in retrograde transport in the cilium and has a role in intraflagellar transport, a process required for ciliary/flagellar assembly. Mutations in this gene cause a heterogeneous spectrum of conditions related to altered primary cilium function and often involve polydactyly, abnormal skeletogenesis, and polycystic kidneys. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jan 2010]

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