Human MTRFR activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MTRFR
Locus ID	91574
Kit Components	GA114125G1, MTRFR gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114125G2, MTRFR gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114125G3, MTRFR gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001143905, NM_001194995, NM_152269
Synonyms	COXPD7; SPG55
Summary	This nuclear gene encodes a mitochondrial matrix protein that appears to contribute to peptide chain termination in the mitochondrial translation machinery. Two different 1 bp deletions (resulting in the same premature stop codon)result in decreased mitochondrial translation, decreased levels of oxidative phosphorylation complexes and encepthalomyopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]

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