Human MPRA (PAQR7) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PAQR7
Locus ID	164091
Kit Components	GA116104G1, MPRA gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116104G2, MPRA gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116104G3, MPRA gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_178422
Synonyms	MPRA; mSR; PGLP
Summary	Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432). Seems to act through a G(i) mediated pathway (PubMed:23763432). May be involved in oocyte maturation (PubMed:12601167). Involved in neurosteroid inhibition of apoptosis (PubMed:23161870). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23161870).[UniProtKB/Swiss-Prot Function]

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