Human SH3PXD2B activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SH3PXD2B
Locus ID	285590
Kit Components	GA117238G1, SH3PXD2B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117238G2, SH3PXD2B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117238G3, SH3PXD2B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001017995, NM_001308175
Synonyms	FAD49; FTHS; HOFI; KIAA1295; TKS4; TSK4
Summary	This gene encodes an adapter protein that is characterized by a PX domain and four Src homology 3 domains. The encoded protein is required for podosome formation and is involved in cell adhesion and migration of numerous cell types. Mutations in this gene are the cause of Frank-ter Haar syndrome (FTHS), and also Borrone Dermato-Cardio-Skeletal (BDCS) syndrome. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015]

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