Mouse Alox12e activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Alox12e
Locus ID	11685
Kit Components	GA200166G1, Alox12e gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200166G2, Alox12e gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200166G3, Alox12e gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_145684
Synonyms	8-LOX; Alox12-ps1; Alox12-ps2; Aloxe; AW259591; e-LOX1
Summary	Non-heme iron-containing dioxygenase that probably catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. May preferentially convert arachidonic acid to (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE.[UniProtKB/Swiss-Prot Function]

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