Mouse M6pr activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	M6pr
Locus ID	17113
Kit Components	GA202536G1, M6pr gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202536G2, M6pr gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202536G3, M6pr gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_010749
Synonyms	CD-MPR; Mpr46
Summary	Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.[UniProtKB/Swiss-Prot Function]

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