Mouse Nck2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nck2
Locus ID	17974
Kit Components	GA202841G1, Nck2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202841G2, Nck2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202841G3, Nck2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_010879
Synonyms	4833426I10Rik; Grb4; Nck-2; NCKbeta
Summary	Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling (By similarity).[UniProtKB/Swiss-Prot Function]

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