Mouse Npas1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Npas1
Locus ID	18142
Kit Components	GA202943G1, Npas1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202943G2, Npas1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202943G3, Npas1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008718
Synonyms	bHLHe11; MOP5
Summary	May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level. Forms a heterodimer that binds core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) leading to transcriptional repression on its target gene TH (PubMed:27782878).[UniProtKB/Swiss-Prot Function]

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