Mouse Pirb activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pirb
Locus ID	18733
Kit Components	GA203230G1, Pirb gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203230G2, Pirb gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203230G3, Pirb gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011095, NM_001357394
Synonyms	Gp91; Lilrb3; LIR-3; PIR-B
Summary	May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).[UniProtKB/Swiss-Prot Function]

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