Mouse Sycp3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sycp3
Locus ID	20962
Kit Components	GA204178G1, Sycp3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204178G2, Sycp3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204178G3, Sycp3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011517
Synonyms	Cor1; Scp3
Summary	Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase (PubMed:11311943, PubMed:22761579). Required for centromere pairing during meiosis in male germ cells (PubMed:22761579). Required for normal meiosis during spermatogenesis and male fertility (PubMed:10678170). Plays a lesser role in female fertility (PubMed:10678170, PubMed:12004129). Required for efficient phosphorylation of HORMAD1 and HORMAD2 (PubMed:22346761).[UniProtKB/Swiss-Prot Function]

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