Mouse Traf4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Traf4
Locus ID	22032
Kit Components	GA204437G1, Traf4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204437G2, Traf4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204437G3, Traf4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009423
Synonyms	A530032M13Rik; CART1; msp2
Summary	Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions (By similarity). Required for normal skeleton development, and for normal development of the respiratory tract.[UniProtKB/Swiss-Prot Function]

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